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Abstract
Direct composite resins have the potential to offer a reasonably predictable alternative to amalgam and other metal-based restoratives. This assumes they are utilized in the appropriate clinical situation and are properly placed. In fact, the increasing demand for tooth-colored restorations, conservation of tooth structure, and cosmetic dental procedures has encouraged the widespread placement of direct composite restorations.2-4 The greater level of clinical success with direct composites is most likely related to material developments, improved clinical skills and techniques, and dramatic advances in adhesive technology.5 Since the use of directly placed composites is a mainstay in the majority of restorative practices, it is imperative that dentists understand the rationale for specific clinical techniques, as well as material idiosyncrasies, in order to optimize the adhesive interface between the composite restorative and the tooth substrate. The majority of direct composites utilized in restorative dentistry today consists of a methacrylated resin matrix (ie, usually a blend of several resins) that is mixed with various glass filler particles, pigments, stabilizers, and chemical and/or light activated initiators. The filler particles in composites are typically silanated. Silane serves as a coupling agent between organics (ie, the resin matrix) and inorganics (ie, the glass fillers). Filler particles can be manufactured in various shapes and sizes and from any number of inorganic glasses (eg, silica, zirconia-silica, barium silicate, lithium, strontium, and ytterbium). As a generalization, larger particle, more heavily filled composites have superior physical properties while smaller particle composites, such as microfills, are not as strong but have a tendency to wear and polish better.6 While an in-depth discussion and characterization of composite chemistry and classification is beyond the scope of this particular paper, clinicians should be aware that the specific nature of the composite being utilized has a direct bearing on what is occurring at the adhesive interface. For example, all current composite formulations shrink to some degree during polymerization (ie, generally 1.5% to 5% by volume). The total amount of shrinkage, the rate of shrinkage, and the elastic modulus (ie, stiffness) of the composite are just some of the factors that influence the degree of stress and strain (ie, deformation) induced at the adhesive interface during composite polymerization. When placing a direct composite, the actual linkage between composite and the tooth tissues is usually mediated through the use of a dentin bonding agent. The development of practical adhesive dentistry can be traced to Michael Buonocore who, in 1955, discovered he could increase the retention of acrylic-based restoratives by first treating the teeth with phosphoric acid.7 Subsequent research by Buonocore, Gwinnett, and Matsui elucidated the mechanism of adhesion between enamel and resin restoratives via resin tag formation.8 Long-term bonding to phosphoric acid-etched enamel surfaces has proven to be highly reliable and predictable; long-term bonding to dentin is not as predictable, regardless of the dentin bonding agent used. Clinicians can generally bond predictably to enamel, but not nearly as predictably to dentin because of the morphologic, histologic, and compositional differences between the two substrates.9 For one thing, dentin is a highly variable substrate. Superficial, middle, and deep dentin can vary significantly in their structural and chemical composition. Enamel, on the other hand, is quite consistent throughout and is also considerably more mineralized than dentin. The inorganic content of mature enamel is approximately 96% hydroxyapatite by weight; the remainder consists of water and organic material. Dentin, on the other hand, is approximately 70% hydroxyapatite by weight, 18% organic material (ie, predominantly collagen), and 12% water.1,10 These percentages are not consistent and can vary significantly depending on a number of factors, including dentin depth, age of the teeth, and history of tooth trauma and/or pathology. This, coupled with the relatively high water content of dentin, presents a significant challenge for consistent and reliable long-term bonding. However, this does not mean that stable and strong initial bonds to dentin cannot be attained. Laboratory studies have shown that many current adhesive systems are capable of producing bond strengths to dentin that equal or surpass those of acid-etched enamel controls. The problem is that most of these are short-term studies (ie, often 24 hours) and the focus needs to be on long-term studies. It is of concern that the literature is replete with longer-term studies—both in vitro and in vivo—that demonstrate a worrisome trend toward eventual degradation of the dentin/adhesive interface.11-18 This could contribute to the observed clinical problem of porcelain veneers sometimes debonding over time when preparations are largely in dentin. Rarely is veneer debonding a problem when significant amounts of enamel remain.19 Microleakage, nanoleakage, hydrolysis, dentin permeability, pulpal pressure, shrinkage stress, “water tree” formation, insufficient hybrid layer formation, phase separation, dentin tubule orientation, occlusion, enzymes released by bacteria, and operator error have all been implicated as potential causes of deterioration of the dentin/adhesive interface over time.20-25 When placing a direct composite, it makes sense to utilize techniques and materials that, hopefully, will increase their long-term predictability.
Know Your Adhesive System
The fourth generation, or three-step total-etch systems,a-c generally have good long-term clinical track records and are perhaps the most versatile of all the adhesive categories because they can be employed for virtually any bonding protocol (ie, direct, indirect, self-cure, dual-cure, light-cure). These systems are still the “gold standard” by which the newer systems are judged. Indeed, none of the newer systems in the marketplace today perform any better, and often perform worse, than the original multiple component total-etch systems of 15 years ago if bond strength to dentin/enamel, microleakage, and long-term durability are used as the evaluation criteria.16 The fifth generation, or two-step total-etch systems,d-i evolved from the desire to simplify the three-step total-etch system protocol. As a group, these are among the most popular systems presently being utilized in dentistry. They have generally proven to be highly effective, simpler, and faster than their multiple component predecessors. On the down side, many in this category, albeit with some exceptions, are not as predictable as the three-step total-etch systems when it comes to bonding to self- and dual-cure composites.26 In addition, the two-step total-etch systems may be more susceptible to water degradation over time than three-step total-etch systems.27 This is because the polymerized primer of the two-step systems tends to be hydrophilic in nature. When using a three-step system, the hydrophilic primer is covered by a more hydrophobic resin, making it less susceptible to water sorption.21 If the clinician elects to utilize a fourth and fifth generation total-etch system in the placement of a direct composite, he or she needs to be aware that the majority of laboratory studies show that these types of systems perform best when placed on moist dentin. This has been termed “wet” bonding,28-30 although moist bonding may be a more accurate description of the phenomena. Dentin exposed to phosphoric acid results in dissolution of the inorganic hydroxyapatite matrix. As the matrix dissolves, the collagen fibrils, which are inherent in dentin, become exposed as they are no longer supported and surrounded by their inorganic scaffolding. It is this friable “collagen network” that must be infiltrated by subsequently placed primers and resins to ensure good bonding. Air-drying of acid-etched dentin causes collapse of the collagen network and interferes with subsequent primer/resin infiltration.31 In dentin that is left moist (eg, after acid conditioning), the collagen fibrils remain in a relatively “open” state and appear to be more permeable to subsequently placed primers and resins. The author’s recommended technique when utilizing a total-etch protocol on unlined dentin is not to air-dry the dentin once the phosphoric acid conditioner is washed off. The excess water is simply blotted out with cotton pellets prior to placing the primer. This results in a visibly moist dentin surface instead of “puddles” of water, which should be avoided.32,33 It warrants noting that some total-etch systems, usually those that are acetone-based, appear to be more sensitive to this wet/dry dentin issue than others (eg, alcohol/water based systems). This highlights an inherent ambiguity many have with the concept of wet bonding, namely exactly how wet is wet? Perhaps the biggest advantage of the sixth generation, or two-component, self-etching systemsj-n is that their efficacy appears to be less dependent on the hydration state of the dentin than total-etch systems. Since the dentin is not pretreated with phosphoric acid—as is the case with total-etch systems—no exposed collagen layer is present to collapse on air-drying prior to placement of the self-etching primers. Clinically this means that “wet” bonding is not a concern and the tooth surface can be briefly air-dried prior to placing a self-etching primer. This is not to say that self-etch systems perform any better than total-etch systems, but they seem to be less technique sensitive in this regard. One could also argue that a possible advantage of a self-etching system is that demineralization of the dentin occurs concurrently with primer infiltration. In principle this helps ensure that the entire zone of demineralization is saturated with primer where it can then be polymerized in situ. On the down side, many products in this category do not etch enamel as well as their total-etch cousins34 and many are not compatible with self- and dual-cure composites.26 A common clinical technique reported by many employing one of the popular self-etching systemsj is to first etch the enamel with traditional phosphoric acid prior to using it. This helps ensure good bond strength to enamel but it does require an additional step in the bonding protocol. Those utilizing this technique should take care to confine the phosphoric acid solely to the enamel. Additional etching of the dentin with phosphoric acid could, in principle, create an “over-etch” situation where the demineralization zone is too deep for subsequently placed primers to completely penetrate. The seventh generation, or one-bottle self-etching systems,o-s represents the latest simplification of adhesive systems. With these systems all the ingredients required for bonding are placed in, and delivered from, a single bottle. This greatly simplifies the bonding protocol. However, the price for simplification may be compromise. Incorporating and placing all of the chemistry required for a viable adhesive system into a single bottle, and having it remain stable over a reasonable period of time, poses a significant challenge. These inherently acidic systems tend to have a significant amount of water in their formulations and may be prone to hydrolysis and chemical breakdown.35,36 In addition, once placed and polymerized, they are generally more hydrophilic than two-step self-etching systems, which makes them more prone to water sorption.37 This could contribute to hydrolysis and degradation of the adhesive interface,38 as well as a reduction in mechanical properties of the composite restorative.39 The acidic nature of the polymerized primers in seventh generation adhesives generally makes them unsuitable for use with self-cure composites since their acidic nature degrades the tertiary aromatic amines required for chemical polymerization of self-cure composites.37,40,41 It is this author’s opinion that while offering ease and simplicity, seventh generation adhesive systems should be used cautiously until more independent research clearly demonstrates their short- and long-term effectiveness. In principle, the “ideal” adhesive system would be one that is hydrophilic when first placed in order to interact with dentin, which inherently has a high water content, but then becomes completely hydrophobic once polymerized in order to discourage water sorption and hydrolysis. Unfortunately, no such chemistry currently exists. A new, recently introduced total-etch systemt is among the first to address this issue by utilizing chemistries that are less hydrophilic in nature.
Flowable Composite Liners
RMGI Liners
Don’t Forget the Small Details—WHICH
REALLY AREN’T THAT SMALL
The author’s personal preference in the placement of direct composites is to utilize a two-step total-etch systemd in conjunction with a RMGI lineru. The entire issue of wet bonding becomes less of a concern with this technique because a significant portion of the exposed dentin is covered by the RMGI liner prior to placing the phosphoric acid and resin primer.
The clinical technique is described below:
Conclusion
References
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